Effect of acute administration of ketamine and imipramine on creatine kinase activity in the brain of rats Efeito da administração aguda da cetamina e imipramina sobre a atividade da creatina quinase no encéfalo de ratos

Effect of acute administration of ketamine and imipramine on creatine kinase activity in the brain of rats Efeito da administração aguda da cetamina e imipramina sobre a atividade da creatina quinase no encéfalo de ratos

OBJECTIVE: Clinical findings suggest that ketamine may be used for the treatment of major depression. The present study aimed to compare behavioral effects and brain Creatine kinase activity in specific brain regions after administration of ketamine and imipramine in rats. METHOD: Rats were acutely...

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Bibliographic Details
Main Authors: Lara C. Assis, Gislaine T. Rezin, Clarissa M. Comim, Samira S. Valvassori, Isabela C. Jeremias, Alexandra I. Zugno, João Quevedo, Emilio L. Streck
Format: Article
Language:English
Published: Associação Brasileira de Psiquiatria (ABP) 2009-09-01
Series:Brazilian Journal of Psychiatry
Subjects:
Imipramina
Creatina quinase
Depressão
Encéfalo
Ratos
Imipramine
Creatine kinase
Depression
Brain
Rats
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462009000300010

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-44462009000300010

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