Development of Multispecies Recombinant Nucleoprotein-Based Indirect ELISA for High-Throughput Screening of Crimean-Congo Hemorrhagic Fever Virus-Specific Antibodies

Development of Multispecies Recombinant Nucleoprotein-Based Indirect ELISA for High-Throughput Screening of Crimean-Congo Hemorrhagic Fever Virus-Specific Antibodies

Crimean-Congo hemorrhagic fever (CCHF) is a re-emerging zoonotic viral disease prevalent in many parts of Asia, Europe, and Africa. The causative agent, Crimean-Congo hemorrhagic fever orthonairovirus (CCHFV), is transmitted through hard ticks. Tick vectors especially belonging to the Hyalomma speci...

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Bibliographic Details
Main Authors: Neha Shrivastava, Ambuj Shrivastava, Sandeep M. Ninawe, Shashi Sharma, Jyoti S. Kumar, Syed Imteyaz Alam, Amit Kanani, Sushil Kumar Sharma, Paban Kumar Dash
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-08-01
Series:Frontiers in Microbiology
Subjects:
Crimean-Congo hemorrhagic fever
antigen
protein purification
IgG
seroepidemiology
diagnosis
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.01822/full

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https://www.frontiersin.org/article/10.3389/fmicb.2019.01822/full

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