Apremilast exerts protective effects on stroke outcomes and blood–brain barrier (BBB) dysfunction through regulating Rho‐associated protein kinase 2 expression

Abstract Aims Stroke is a devastating event and a huge public health concern worldwide. Apremilast (APR) is a selective inhibitor of phosphodiesterase‐4 involved in various neurological diseases, including stroke. However, the protective effects of APR on stroke have not been investigated. Here, we...

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Bibliographic Details
Main Authors: Mingyuan Wang, Xiangyuan Meng, Zhihua Cheng
Format: Article
Language:English
Published: Wiley 2022-09-01
Series:Brain and Behavior
Subjects:
Online Access:https://doi.org/10.1002/brb3.2677