Improving the Diagnosis of Bacterial Infections: Evaluation of 16S rRNA Nanopore Metagenomics in Culture-Negative Samples

Improving the Diagnosis of Bacterial Infections: Evaluation of 16S rRNA Nanopore Metagenomics in Culture-Negative Samples

While 16S rRNA PCR-Sanger sequencing has paved the way for the diagnosis of culture-negative bacterial infections, it does not provide the composition of polymicrobial infections. We aimed to evaluate the performance of the Nanopore-based 16S rRNA metagenomic approach, using both partial and full-le...

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Bibliographic Details
Main Authors: Coralie Bouchiat, Christophe Ginevra, Yvonne Benito, Tiphaine Gaillard, Hélène Salord, Olivier Dauwalder, Frédéric Laurent, François Vandenesch
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Microbiology
Subjects:
metagenomics
bacterial infections
molecular diagnosis
Nanopore sequencing
16S rRNA
Online Access:https://www.frontiersin.org/articles/10.3389/fmicb.2022.943441/full

Internet

https://www.frontiersin.org/articles/10.3389/fmicb.2022.943441/full

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