Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability

Fixed-dose combination orally disintegrating tablets to treat cardiovascular disease: formulation, in vitro characterization and physiologically based pharmacokinetic modeling to assess bioavailability

Thomas J Dennison,1 Julian C Smith,2 Raj K Badhan,1 Afzal R Mohammed1 1Aston School of Pharmacy, Aston University, Birmingham, 2Viridian Pharma Ltd, Newport, UK Abstract: Cardiovascular disease (CVD) is the leading cause of death among men and women worldwide. In CVD, hypertension and dyslipidemia...

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Bibliographic Details
Main Authors: Dennison TJ, Smith JC, Badhan RK, Mohammed AR
Format: Article
Language:English
Published: Dove Medical Press 2017-03-01
Series:Drug Design, Development and Therapy
Subjects:
Orally disintegrating tablet
Fixed dose combination
Cardiovascular disease
Physiologically based pharmacokinetic modelling
Bioavailability
Bioequivalence
Online Access:https://www.dovepress.com/fixed-dose-combination-orally-disintegrating-tablets-to-treat-cardiova-peer-reviewed-article-DDDT

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https://www.dovepress.com/fixed-dose-combination-orally-disintegrating-tablets-to-treat-cardiova-peer-reviewed-article-DDDT

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