A hominoid-specific signaling axis regulating the tempo of synaptic maturation

Summary: Human cortical neurons (hCNs) exhibit high dendritic complexity and synaptic density, and the maturation process is greatly protracted. However, the molecular mechanism governing these specific features remains unclear. Here, we report that the hominoid-specific gene TBC1D3 promotes dendrit...

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Bibliographic Details
Main Authors: Jian Dong, Xiao-Na Zhu, Peng-Ming Zeng, Dong-Dong Cao, Yang Yang, Ji Hu, Zhen-Ge Luo
Format: Article
Language:English
Published: Elsevier 2024-08-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724008775