Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool

Patients with isolated REM-sleep behavior disorder have elevated levels of alpha-synuclein aggregates in stool

Abstract Misfolded and aggregated α-synuclein is a neuropathological hallmark of Parkinson’s disease (PD). Thus, α-synuclein aggregates are regarded as a biomarker for the development of diagnostic assays. Quantification of α-synuclein aggregates in body fluids is challenging, and requires highly se...

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Bibliographic Details
Main Authors: Anja Schaffrath, Sophia Schleyken, Aline Seger, Hannah Jergas, Pelin Özdüzenciler, Marlene Pils, Lara Blömeke, Anneliese Cousin, Johannes Willbold, Tuyen Bujnicki, Oliver Bannach, Gereon R. Fink, Dieter Willbold, Michael Sommerauer, Michael T. Barbe, Gültekin Tamgüney
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:npj Parkinson's Disease
Online Access:https://doi.org/10.1038/s41531-023-00458-4

Internet

https://doi.org/10.1038/s41531-023-00458-4

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