Voluntary wheel running alters markers of amyloid-beta precursor protein processing in an ovarian hormone depleted model

Voluntary wheel running alters markers of amyloid-beta precursor protein processing in an ovarian hormone depleted model

IntroductionAberrant cleavage of the transmembrane protein, amyloid-beta precursor protein (ABPP), results in the overproduction of amyloid-beta (AB) peptides which can form senile plaques in the brain. These plaques can get lodged within synapses and disrupt neuronal communication ultimately leadin...

Full description

Bibliographic Details
Main Authors: Ahmad Mohammad, Michael S. Finch, Jacob Sweezey-Munroe, Rebecca E. K. MacPherson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-12-01
Series:Frontiers in Endocrinology
Subjects:
physical activity
brain derived neurotrophic factor
estrogen
beta-secretase
Alpha-secretase
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.1069404/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2022.1069404/full

Similar Items