Predicting and affecting response to cancer therapy based on pathway-level biomarkers

Predicting and affecting response to cancer therapy based on pathway-level biomarkers

Predicting an individual's response to therapy is an important goal for precision medicine. Here, the authors use an algorithm that takes into account the interaction type and directionality of signalling pathways in protein–protein interactions and find that their pathway analysis can predict...

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Bibliographic Details
Main Authors: Rotem Ben-Hamo, Adi Jacob Berger, Nancy Gavert, Mendy Miller, Guy Pines, Roni Oren, Eli Pikarsky, Cyril H. Benes, Tzahi Neuman, Yaara Zwang, Sol Efroni, Gad Getz, Ravid Straussman
Format: Article
Language:English
Published: Nature Portfolio 2020-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-17090-y

Internet

https://doi.org/10.1038/s41467-020-17090-y

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