Indoleamine 2,3-Dioxygenase as a Therapeutic Target for Alzheimer’s Disease and Geriatric Depression

Neuroimmune-triggered neuroinflammation of the central nervous system is emerging as an important aetiopathogenic factor for multiple neurological disorders, including depression, dementia, Alzheimer’s disease, multiple sclerosis and others. Tryptophan metabolism via the kynurenic pathway, which is...

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Bibliographic Details
Main Authors: Karl Savonije, Autumn Meek, Donald F. Weaver
Format: Article
Language:English
Published: MDPI AG 2023-05-01
Series:Brain Sciences
Subjects:
Online Access:https://www.mdpi.com/2076-3425/13/6/852