STIM1 and STIM2‐mediated Ca2+ influx regulates antitumour immunity by CD8+ T cells
Abstract Store‐operated calcium entry (SOCE) through Ca2+ release‐activated Ca2+ (CRAC) channels regulates the function of many immune cells. Patients with loss‐of‐function mutations in the CRAC channel genes ORAI1 or STIM1 are immunodeficient and are prone to develop virus‐associated tumours. This...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
| Published: |
Springer Nature
2013-08-01
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| Series: | EMBO Molecular Medicine |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/emmm.201302989 |