Proteogenomic network analysis reveals dysregulated mechanisms and potential mediators in Parkinson’s disease

Abstract Parkinson’s disease is highly heterogeneous across disease symptoms, clinical manifestations and progression trajectories, hampering the identification of therapeutic targets. Despite knowledge gleaned from genetics analysis, dysregulated proteome mechanisms stemming from genetic aberration...

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Bibliographic Details
Main Authors: Abolfazl Doostparast Torshizi, Dongnhu T. Truong, Liping Hou, Bart Smets, Christopher D. Whelan, Shuwei Li
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-024-50718-x