Development of an In Vitro 3D Model for Investigating Ligamentum Flavum Hypertrophy

Development of an In Vitro 3D Model for Investigating Ligamentum Flavum Hypertrophy

Abstract Background Ligamentum flavum hypertrophy (LFH) is among the most crucial factors in degenerative lumbar spinal stenosis, which can cause back pain, lower extremity pain, cauda equina syndrome and neurogenic claudication. The exact pathogenesis of LFH remains elusive despite extensive resear...

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Bibliographic Details
Main Authors: Cheng-Li Lin, Yi-Ting Kuo, Che-Hao Tsao, Yan-Jye Shyong, Shu-Hsien Shih, Ting-Yuan Tu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Biological Procedures Online
Subjects:
Lumbar spinal stenosis
Ligamentum flavum
Ligamentum flavum hypertrophy
3D cell culture
Spheroid
Online Access:http://link.springer.com/article/10.1186/s12575-020-00132-6

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http://link.springer.com/article/10.1186/s12575-020-00132-6

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