Pharmacokinetics of mycophenolic acid and its effect on CD4+ and CD8+ T cells after oral administration of mycophenolate mofetil to healthy cats

Abstract Background Mycophenolate mofetil (MMF) is an immunosuppressant used in human and veterinary medicine. Little pharmacokinetic and pharmacodynamic information on MMF is available in cats. Objective To evaluate the plasma disposition of mycophenolic acid (MPA) and assess its effect on total pe...

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Автори: Jennifer E. Slovak, Julianne K. Hwang, Sol M. Rivera, Nicolas F. Villarino
Формат: Стаття
Мова:English
Опубліковано: Wiley 2019-09-01
Серія:Journal of Veterinary Internal Medicine
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Онлайн доступ:https://doi.org/10.1111/jvim.15585