Mice with a naturally occurring DISC1 mutation display a broad spectrum of behaviors associated to psychiatric disorders

DISC1 (disrupted in schizophrenia-1) gene is associated with several neuropsychiatric disorders as it is disrupted by a balanced translocation involving chromosomes 1 and 11 in a large Scottish pedigree with high prevalence of schizophrenia, bipolar disorder and major depression. Since its identific...

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Bibliographic Details
Main Authors: Raquel eGomez-Sintes, Mirna eKvajo, Joseph A Gogos, Jose J Lucas
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00253/full