Vitamin D Receptor Mediates Attenuating Effect of Lithocholic Acid on Dextran Sulfate Sodium Induced Colitis in Mice

Vitamin D Receptor Mediates Attenuating Effect of Lithocholic Acid on Dextran Sulfate Sodium Induced Colitis in Mice

Bile acids are major components of bile; they emulsify dietary lipids for efficient digestion and absorption and act as signaling molecules that activate nuclear and membrane receptors. The vitamin D receptor (VDR) is a receptor for the active form of vitamin D and lithocholic acid (LCA), a secondar...

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Bibliographic Details
Main Authors: Hitomi Kubota, Michiyasu Ishizawa, Makoto Kodama, Yoshihiro Nagase, Shigeaki Kato, Makoto Makishima, Kenichi Sakurai
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:International Journal of Molecular Sciences
Subjects:
vitamin D receptor
lithocholic acid
bile acid
inflammatory bowel disease
dextran sulfate sodium
intestinal mucosal injury
Online Access:https://www.mdpi.com/1422-0067/24/4/3517

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https://www.mdpi.com/1422-0067/24/4/3517

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