Metformin Reduces Potassium Currents and Prolongs Repolarization in Non-Diabetic Heart

Metformin Reduces Potassium Currents and Prolongs Repolarization in Non-Diabetic Heart

Metformin is the first choice drug for the treatment of type 2 diabetes due to positive results in reducing hyperglycaemia and insulin resistance. However, diabetic patients have higher risk of ventricular arrhythmia and sudden cardiac death, and metformin failed to reduce ventricular arrhythmia in...

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Bibliographic Details
Main Authors: Layse Malagueta-Vieira, Julieta Fernández-Ruocco, María P. Hortigón-Vinagre, Víctor Zamora, Julián Zayas-Arrabal, Leyre Echeazarra, Godfrey L. Smith, Martín Vila Petroff, Emiliano Medei, Óscar Casis, Mónica Gallego
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:International Journal of Molecular Sciences
Subjects:
cardiac electrophysiology
repolarization
cardiomyocyte
ion channels
ventricular arrhythmia
cardiac action potential
Online Access:https://www.mdpi.com/1422-0067/23/11/6021

Internet

https://www.mdpi.com/1422-0067/23/11/6021

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