A real-life treatment cohort of pancreatic neuroendocrine tumors: High-grade increase in metastases confers poor survival

A real-life treatment cohort of pancreatic neuroendocrine tumors: High-grade increase in metastases confers poor survival

BackgroundTumor grade determined by the Ki67 index is the best prognostic factor for pancreatic neuroendocrine tumors (PanNETs). However, we often observe that the grade of metastases differs from that of their primary tumors. This study aimed to investigate the frequency of grade changes between pr...

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Bibliographic Details
Main Authors: Wu-Hu Zhang, He-Li Gao, Wen-Sheng Liu, Yi Qin, Zeng Ye, Xin Lou, Fei Wang, Yue Zhang, Xue-Min Chen, Jie Chen, Xian-Jun Yu, Qi-Feng Zhuo, Xiao-Wu Xu, Shun-Rong Ji
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Endocrinology
Subjects:
pancreatic neuroendocrine tumors
Ki67 index variation
grade increase
preoperative neoadjuvant treatment
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.941210/full

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https://www.frontiersin.org/articles/10.3389/fendo.2022.941210/full

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