Ramelteon alleviates myocardial ischemia/reperfusion injury (MIRI) through Sirt3-­dependent regulation of cardiomyocyte apoptosis

Ramelteon alleviates myocardial ischemia/reperfusion injury (MIRI) through Sirt3-­dependent regulation of cardiomyocyte apoptosis

Reperfusion stands as a pivotal intervention for ischemic heart disease. However, the restoration of blood flow to ischemic tissue always lead to further damage, which is known as myocardial ischemia/reperfusion injury (MIRI). Ramelteon is an orally administered drug used to improve sleep quality, w...

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Bibliographic Details
Main Authors: Zhenbo Yang, Yilin Xie, Mengyang Li, Wenxian Chen, Changsheng Zhong, Jin Ju, Qin Deng, Huifang Wang, Ting Cheng, Lei Zhang, Weijie Du, Haihai Liang
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ramelteon
Myocardial ischemia/reperfusion injury
Sirt3
Cardiomyocyte apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332224001100

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http://www.sciencedirect.com/science/article/pii/S0753332224001100

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