C-Ring Oxidized Estrone Acetate Derivatives: Assessment of Antiproliferative Activities and Docking Studies

C-Ring Oxidized Estrone Acetate Derivatives: Assessment of Antiproliferative Activities and Docking Studies

C-Ring oxidized estrone acetate derivatives as antiproliferative agents were prepared and tested against five cancer cell lines by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide assay. Flow cytometry assays to evaluate cell viability and modifications in cell cycle phases and molec...

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Bibliographic Details
Main Authors: Catarina Canário, Mariana Matias, Vanessa Brito, Patrícia Pires, Adriana O. Santos, Amílcar Falcão, Samuel Silvestre, Gilberto Alves
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Applied Sciences
Subjects:
estrone
C-ring
cytotoxic
estrogenicity
docking
Online Access:https://www.mdpi.com/2076-3417/12/7/3579

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https://www.mdpi.com/2076-3417/12/7/3579

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