Effects of Everolimus in Modulating the Host Immune Responses against <i>Mycobacterium tuberculosis</i> Infection

Effects of Everolimus in Modulating the Host Immune Responses against <i>Mycobacterium tuberculosis</i> Infection

The phosphoinositide 3-kinase/protein kinase B/mammalian target of rapamycin (P13K/AKT/mTOR) pathway plays a key role in tuberculosis (TB) pathogenesis and infection. While the activity levels of this pathway during active infection are still debated, manipulating this pathway shows potential benefi...

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Bibliographic Details
Main Authors: Anmol Raien, Sofia Davis, Michelle Zhang, David Zitser, Michelle Lin, Graysen Pitcher, Krishna Bhalodia, Selvakumar Subbian, Vishwanath Venketaraman
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Cells
Subjects:
<i>Mycobacterium tuberculosis</i>
everolimus
mTOR
autophagy
host-directed therapy
Online Access:https://www.mdpi.com/2073-4409/12/22/2653

Internet

https://www.mdpi.com/2073-4409/12/22/2653

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