Viral Traits and Cellular Knock-Out Genotype Affect Dependence of BVDV on Bovine CD46

The role of bovine CD46 in the host cell entry of BVDV has been established for more than a decade. By generating novel MDBK CD46 knock-out clones, we confirm previously reported data on the CD46 motives important for BVDV binding and the importance of the G479R exchange within BVDV E<sup>rns&...

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Bibliographic Details
Main Authors: Hann-Wei Chen, Verena Huber, Kati Szakmary-Braendle, Kerstin Seitz, Marlene Moetz, Till Ruemenapf, Christiane Riedel
Format: Article
Language:English
Published: MDPI AG 2021-12-01
Series:Pathogens
Subjects:
Online Access:https://www.mdpi.com/2076-0817/10/12/1620