The Capacity of Drug-Metabolising Enzymes in Modulating the Therapeutic Efficacy of Drugs to Treat Rhabdomyosarcoma

The Capacity of Drug-Metabolising Enzymes in Modulating the Therapeutic Efficacy of Drugs to Treat Rhabdomyosarcoma

Rhabdomyosarcoma (RMS) is a rare soft tissue sarcoma (STS) that predominantly affects children and teenagers. It is the most common STS in children (40%) and accounts for 5–8% of total childhood malignancies. Apart from surgery and radiotherapy in eligible patients, standard chemotherapy is the only...

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Bibliographic Details
Main Authors: Enric Arasanz Picher, Muhammad Wahajuddin, Stefan Barth, Julia Chisholm, Janet Shipley, Klaus Pors
Format: Article
Language:English
Published: MDPI AG 2024-02-01
Series:Cancers
Subjects:
rhabdomyosarcoma
drug-metabolizing enzymes
cytochrome P450
aldehyde dehydrogenase
carboxyl esterase
cyclophosphamide
Online Access:https://www.mdpi.com/2072-6694/16/5/1012

Internet

https://www.mdpi.com/2072-6694/16/5/1012

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