Refinement of the spinal cord injury rat model and validation of its applicability as a model for memory loss and chronic pain

Refinement of the spinal cord injury rat model and validation of its applicability as a model for memory loss and chronic pain

Background: Laminectomy produces trauma in spinal cord injury (SCI) animal models resulting in impinging artefacts and welfare issues. Mechanizing laminectomy using a dental burr assisted (DBA) technique to reduce the impact of conventionally performed laminectomy on animal welfare without any alter...

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Bibliographic Details
Main Authors: V.S. Harikrishnan, Hamza Palekkodan, Ansar Fasaludeen, Lissy K. Krishnan, Klas S.P. Abelson
Format: Article
Language:English
Published: Elsevier 2021-07-01
Series:Heliyon
Subjects:
Dental burr assisted laminectomy
Refinement
Spinal cord injury
BBB score
Rat model
Chronic pain
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844021016030

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http://www.sciencedirect.com/science/article/pii/S2405844021016030

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