Endocytosis and Endosomal Trafficking of DNA After Gene Electrotransfer In Vitro

Endocytosis and Endosomal Trafficking of DNA After Gene Electrotransfer In Vitro

DNA electrotransfer is a successful technique for gene delivery into cells and represents an attractive alternative to virus-based methods for clinical applications including gene therapy and DNA vaccination. However, little is currently known about the mechanisms governing DNA internalization and i...

Full description

Bibliographic Details
Main Authors: Christelle Rosazza, Hendrik Deschout, Annette Buntz, Kevin Braeckmans, Marie-Pierre Rols, Andreas Zumbusch
Format: Article
Language:English
Published: Elsevier 2016-01-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
colocalization
electric field
electroporation
endocytosis
endosomal trafficking
gene electrotransfer
plasmid DNA
single-particle tracking
Online Access:http://www.sciencedirect.com/science/article/pii/S216225311730015X

Internet

http://www.sciencedirect.com/science/article/pii/S216225311730015X

Similar Items