Endothelial Function and Oxidative Stress in X-Linked, gp91phox Deficiency, Chronic Granulomatous Disease

Endothelial Function and Oxidative Stress in X-Linked, gp91phox Deficiency, Chronic Granulomatous Disease

Two patients with X-linked chronic granulomatous disease without NAPDH oxidase activity and with high responses of flow-mediated vasodilation are reported. Bone marrow transplantation restored oxidative stress to the levels of those in healthy subjects and decreased flow-mediated vasodilation to the...

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Bibliographic Details
Main Authors: Yukihito Higashi, MD, PhD, Shinji Kishimoto, MD, PhD, Tatsuya Maruhashi, MD, PhD
Format: Article
Language:English
Published: Elsevier 2020-08-01
Series:JACC: Case Reports
Subjects:
chronic granulomatous disease
endothelial function
gp91phox
NADPH oxidase
nitric oxide
oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2666084920306823

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http://www.sciencedirect.com/science/article/pii/S2666084920306823

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