Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled Trial
<i>Background and Objectives</i>: Obese premenopausal women are at high risk of developing insulin resistance (IR). Concurrent aerobic and strength training (CAST) has been shown to provide remarkable advantages, yet its effects, along with caloric restriction in such a high-risk populat...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2023-06-01
|
| Series: | Medicina |
| Subjects: | |
| Online Access: | https://www.mdpi.com/1648-9144/59/7/1193 |
| _version_ | 1797588375888199680 |
|---|---|
| author | Yasser M. Aneis Ghada E. El Refaye Mona Mohamed Taha Monira I. Aldhahi Hany F. Elsisi |
| author_facet | Yasser M. Aneis Ghada E. El Refaye Mona Mohamed Taha Monira I. Aldhahi Hany F. Elsisi |
| author_sort | Yasser M. Aneis |
| collection | DOAJ |
| description | <i>Background and Objectives</i>: Obese premenopausal women are at high risk of developing insulin resistance (IR). Concurrent aerobic and strength training (CAST) has been shown to provide remarkable advantages, yet its effects, along with caloric restriction in such a high-risk population, are not yet established. This study aimed to investigate the impact of concurrent aerobic and strength training with caloric restriction (CAST-CR) on IR in obese premenopausal women. <i>Materials and Methods</i>: Forty-two obese premenopausal women with reported IR, aged 40–50 years, were randomly allocated to either the (CAST-CR) intervention group, who underwent CAST with caloric restriction, or the (AT-CR) control group, who received aerobic training in addition to caloric restriction. Both groups completed 12 weeks of controlled training with equivalent training time. Aerobic training began at 60% and gradually progressed to achieve 75% of the maximum heart rate, while strength training was executed at 50% to 70% of the one-repetition maximum (1RM). Anthropometric measures, abdominal adiposity, metabolic parameters, and homeostasis model assessment-estimated insulin resistance (HOMA-IR) were evaluated prior to and following the intervention. <i>Results</i>: Both groups experienced a substantial enhancement in the selected parameters compared to the baseline (<i>p</i> < 0.001), with higher improvement within the CAST-CR group. The changes in HOMA-IR were −1.24 (95%CI, −1.37 to −1.12) in the CAST-CR group vs. −1.07 (95%CI, −1.19 to −0.94) in the AT-CR group. <i>Conclusions</i>: While AT-CR improved insulin sensitivity in premenopausal women who were obese and hyperinsulinemic, CAST with calorie restriction improved insulin sensitivity more significantly, suggesting it as a preferable alternative. |
| first_indexed | 2024-03-11T00:52:02Z |
| format | Article |
| id | doaj.art-af5ed594f9f540ec9b4711cbdd5f001d |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-11T00:52:02Z |
| publishDate | 2023-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-af5ed594f9f540ec9b4711cbdd5f001d2023-11-18T20:23:07ZengMDPI AGMedicina1010-660X1648-91442023-06-01597119310.3390/medicina59071193Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled TrialYasser M. Aneis0Ghada E. El Refaye1Mona Mohamed Taha2Monira I. Aldhahi3Hany F. Elsisi4Department of Basic Sciences, Faculty of Physical Therapy, Cairo University, Giza 11432, EgyptDepartment of Physical Therapy for Women’s Health, Faculty of Physical Therapy, Cairo University, Giza 11432, EgyptDepartment of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaDepartment of Rehabilitation Sciences, College of Health and Rehabilitation Sciences, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi ArabiaDepartment of Physical Therapy for Cardiovascular/Respiratory Disorders and Geriatrics, Faculty of Physical Therapy, Cairo University, Giza 11432, Egypt<i>Background and Objectives</i>: Obese premenopausal women are at high risk of developing insulin resistance (IR). Concurrent aerobic and strength training (CAST) has been shown to provide remarkable advantages, yet its effects, along with caloric restriction in such a high-risk population, are not yet established. This study aimed to investigate the impact of concurrent aerobic and strength training with caloric restriction (CAST-CR) on IR in obese premenopausal women. <i>Materials and Methods</i>: Forty-two obese premenopausal women with reported IR, aged 40–50 years, were randomly allocated to either the (CAST-CR) intervention group, who underwent CAST with caloric restriction, or the (AT-CR) control group, who received aerobic training in addition to caloric restriction. Both groups completed 12 weeks of controlled training with equivalent training time. Aerobic training began at 60% and gradually progressed to achieve 75% of the maximum heart rate, while strength training was executed at 50% to 70% of the one-repetition maximum (1RM). Anthropometric measures, abdominal adiposity, metabolic parameters, and homeostasis model assessment-estimated insulin resistance (HOMA-IR) were evaluated prior to and following the intervention. <i>Results</i>: Both groups experienced a substantial enhancement in the selected parameters compared to the baseline (<i>p</i> < 0.001), with higher improvement within the CAST-CR group. The changes in HOMA-IR were −1.24 (95%CI, −1.37 to −1.12) in the CAST-CR group vs. −1.07 (95%CI, −1.19 to −0.94) in the AT-CR group. <i>Conclusions</i>: While AT-CR improved insulin sensitivity in premenopausal women who were obese and hyperinsulinemic, CAST with calorie restriction improved insulin sensitivity more significantly, suggesting it as a preferable alternative.https://www.mdpi.com/1648-9144/59/7/1193aerobic exercisecaloric restrictioninsulin resistancepremenopausestrength training |
| spellingShingle | Yasser M. Aneis Ghada E. El Refaye Mona Mohamed Taha Monira I. Aldhahi Hany F. Elsisi Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled Trial Medicina aerobic exercise caloric restriction insulin resistance premenopause strength training |
| title | Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled Trial |
| title_full | Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled Trial |
| title_fullStr | Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled Trial |
| title_full_unstemmed | Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled Trial |
| title_short | Concurrent Aerobic and Strength Training with Caloric Restriction Reduces Insulin Resistance in Obese Premenopausal Women: A Randomized Controlled Trial |
| title_sort | concurrent aerobic and strength training with caloric restriction reduces insulin resistance in obese premenopausal women a randomized controlled trial |
| topic | aerobic exercise caloric restriction insulin resistance premenopause strength training |
| url | https://www.mdpi.com/1648-9144/59/7/1193 |
| work_keys_str_mv | AT yassermaneis concurrentaerobicandstrengthtrainingwithcaloricrestrictionreducesinsulinresistanceinobesepremenopausalwomenarandomizedcontrolledtrial AT ghadaeelrefaye concurrentaerobicandstrengthtrainingwithcaloricrestrictionreducesinsulinresistanceinobesepremenopausalwomenarandomizedcontrolledtrial AT monamohamedtaha concurrentaerobicandstrengthtrainingwithcaloricrestrictionreducesinsulinresistanceinobesepremenopausalwomenarandomizedcontrolledtrial AT moniraialdhahi concurrentaerobicandstrengthtrainingwithcaloricrestrictionreducesinsulinresistanceinobesepremenopausalwomenarandomizedcontrolledtrial AT hanyfelsisi concurrentaerobicandstrengthtrainingwithcaloricrestrictionreducesinsulinresistanceinobesepremenopausalwomenarandomizedcontrolledtrial |