A drug stabilizable GAL80ds for conditional control of gene expression via GAL4-UAS and CRISPR-Cas9 systems in Drosophila

A drug stabilizable GAL80ds for conditional control of gene expression via GAL4-UAS and CRISPR-Cas9 systems in Drosophila

Abstract The binary GAL4-UAS expression system has been widely used in Drosophila to achieve tissue-specific expression of genes. To further allow for simultaneous spatial and conditional control of gene expression in existing GAL4 expression lines backgrounds, temperature and chemical controllable...

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Bibliographic Details
Main Authors: Vaishnavi Kogenaru, Mark Isalan, Manjunatha Kogenaru
Format: Article
Language:English
Published: Nature Portfolio 2024-03-01
Series:Scientific Reports
Subjects:
Protein design
Transgene expression
Gene function
Gene toxicity
Lethality gene
Online Access:https://doi.org/10.1038/s41598-024-56343-4

Internet

https://doi.org/10.1038/s41598-024-56343-4

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