A drug stabilizable GAL80ds for conditional control of gene expression via GAL4-UAS and CRISPR-Cas9 systems in Drosophila

A drug stabilizable GAL80ds for conditional control of gene expression via GAL4-UAS and CRISPR-Cas9 systems in Drosophila

Abstract The binary GAL4-UAS expression system has been widely used in Drosophila to achieve tissue-specific expression of genes. To further allow for simultaneous spatial and conditional control of gene expression in existing GAL4 expression lines backgrounds, temperature and chemical controllable...

Повний опис

Бібліографічні деталі
Автори: Vaishnavi Kogenaru, Mark Isalan, Manjunatha Kogenaru
Формат: Стаття
Мова:English
Опубліковано: Nature Portfolio 2024-03-01
Серія:Scientific Reports
Предмети:
Protein design
Transgene expression
Gene function
Gene toxicity
Lethality gene
Онлайн доступ:https://doi.org/10.1038/s41598-024-56343-4

Інтернет

https://doi.org/10.1038/s41598-024-56343-4

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