Oxygen Gradient Induced in Microfluidic Chips Can Be Used as a Model for Liver Zonation

Availability of oxygen plays an important role in tissue organization and cell-type specific metabolism. It is, however, difficult to analyze hypoxia-related adaptations in vitro because of inherent limitations of experimental model systems. In this study, we establish a microfluidic tissue culture...

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Bibliographic Details
Main Authors: Shahrouz Ghafoory, Christina Stengl, Stefan Kopany, Mert Mayadag, Nils Mechtel, Brennah Murphy, Sebastian Schattschneider, Niklas Wilhelmi, Stefan Wölfl
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/23/3734