MRSamePopTest: introducing a simple falsification test for the two-sample mendelian randomisation ‘same population’ assumption
Abstract Two-sample MR is an increasingly popular method for strengthening causal inference in epidemiological studies. For the effect estimates to be meaningful, variant-exposure and variant-outcome associations must come from comparable populations. A recent systematic review of two-sample MR stud...
Main Authors: | , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2024-01-01
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Series: | BMC Research Notes |
Subjects: | |
Online Access: | https://doi.org/10.1186/s13104-024-06684-0 |