RANKL immunisation inhibits prostate cancer metastasis by modulating EMT through a RANKL-dependent pathway

Abstract Prostate cancer (PCa) morbidity in the majority of patients is due to metastatic events, which are a clinical obstacle. Therefore, a better understanding of the mechanism underlying metastasis is imperative if we are to develop novel therapeutic strategies. Receptor activator of nuclear fac...

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Bibliographic Details
Main Authors: Mineon Park, Yong Jin Cho, Bora Kim, Young Jong Ko, Yuria Jang, Yeon Hee Moon, Hoon Hyun, Wonbong Lim
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91721-2