Extensive Homoplasy but No Evidence of Convergent Evolution of Repeat Numbers at MIRU Loci in Modern Mycobacterium tuberculosis Lineages

Extensive Homoplasy but No Evidence of Convergent Evolution of Repeat Numbers at MIRU Loci in Modern Mycobacterium tuberculosis Lineages

More human deaths have been attributable to Mycobacterium tuberculosis than any other pathogen, and the epidemic is sustained by ongoing transmission. Various typing schemes have been developed to identify strain-specific differences and track transmission dynamics in affected communities, with rece...

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Bibliographic Details
Main Authors: Alexander C. Outhred, Ulziijargal Gurjav, Peter Jelfs, Nadine McCallum, Qinning Wang, Grant A. Hill-Cawthorne, Ben J. Marais, Vitali Sintchenko
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Public Health
Subjects:
Mycobacterium tuberculosis
homoplasy
convergent evolution
MIRU
VNTR
phylogeny
Online Access:https://www.frontiersin.org/article/10.3389/fpubh.2020.00455/full

Internet

https://www.frontiersin.org/article/10.3389/fpubh.2020.00455/full

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