ATRX proximal protein associations boast roles beyond histone deposition.

The ATRX ATP-dependent chromatin remodelling/helicase protein associates with the DAXX histone chaperone to deposit histone H3.3 over repetitive DNA regions. Because ATRX-protein interactions impart functions, such as histone deposition, we used proximity-dependent biotinylation (BioID) to identify...

Full description

Bibliographic Details
Main Authors: William A Scott, Erum Z Dhanji, Boris J A Dyakov, Ema S Dreseris, Jonathon S Asa, Laura J Grange, Mila Mirceta, Christopher E Pearson, Grant S Stewart, Anne-Claude Gingras, Eric I Campos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-11-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009909