Targeted Minimum Loss-Based Estimation of Causal Effects in Right-Censored Survival Data with Time-Dependent Covariates: Warfarin, Stroke, and Death in Atrial Fibrillation

Targeted Minimum Loss-Based Estimation of Causal Effects in Right-Censored Survival Data with Time-Dependent Covariates: Warfarin, Stroke, and Death in Atrial Fibrillation

Causal effects in right-censored survival data can be formally defined as the difference in the marginal cumulative event probabilities under particular interventions. Conventional estimators, such as the Kaplan-Meier (KM), fail to consistently estimate these marginal parameters under dependent trea...

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Bibliographic Details
Main Authors: Brooks Jordan C., van der Laan Mark J., Singer Daniel E., Go Alan S.
Format: Article
Language:English
Published: De Gruyter 2013-11-01
Series:Journal of Causal Inference
Subjects:
targeted minimum loss-based estimation
survival analysis
dependent right-censoring
efficient influence curve
targeted maximum likelihood estimation
Online Access:https://doi.org/10.1515/jci-2013-0001

Internet

https://doi.org/10.1515/jci-2013-0001

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