Therapeutic hypercapnia for prevention of secondary ischemia after severe subarachnoid hemorrhage: physiological responses to continuous hypercapnia

Abstract Temporary hypercapnia has been shown to increase cerebral blood flow (CBF) and might be used as a therapeutical tool in patients with severe subarachnoid hemorrhage (SAH). It was the aim of this study was to investigate the optimum duration of hypercapnia. This point is assumed to be the ti...

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Bibliographic Details
Main Authors: Christian Stetter, Franziska Weidner, Nadine Lilla, Judith Weiland, Ekkehard Kunze, Ralf-Ingo Ernestus, Ralf Michael Muellenbach, Thomas Westermaier
Format: Article
Language:English
Published: Nature Portfolio 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91007-7