Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism

Guggulsterone Mediated JAK/STAT and PPAR-Gamma Modulation Prevents Neurobehavioral and Neurochemical Abnormalities in Propionic Acid-Induced Experimental Model of Autism

Autism spectrum disorder is a neurodevelopmental disorder marked by repetitive behaviour, challenges in verbal and non-verbal communication, poor socio-emotional health, and cognitive impairment. An increased level of signal transducer and activator of transcription 3 (STAT3) and a decreased level o...

Full description

Bibliographic Details
Main Authors: Rishabh Khera, Sidharth Mehan, Sonalika Bhalla, Sumit Kumar, Abdulrahman Alshammari, Metab Alharbi, Satya Sai Sadhu
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
autism
JAK/STAT
PPAR-gamma
guggulsterone
propionic acid
neuroprotection
Online Access:https://www.mdpi.com/1420-3049/27/3/889

Internet

https://www.mdpi.com/1420-3049/27/3/889

Similar Items