The mechanisms of gastric mucosal injury: focus on initial chief cell loss as a key target

Abstract Diffuse gastric mucosal injury is a chronic injury with altered cell differentiation, including spasmolytic polypeptide expression metaplasia (SPEM) and intestinal metaplasia (IM), which are considered precancerous lesions of gastric cancer (GC). Previously, most studies have focused on how...

Full description

Bibliographic Details
Main Authors: Zilin Deng, Jiaxing Zhu, Zhiyuan Ma, Zhiqiang Yi, Biguang Tuo, Taolang Li, Xuemei Liu
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01318-z