Improving peptide-protein docking with AlphaFold-Multimer using forced sampling
Protein interactions are key in vital biological processes. In many cases, particularly in regulation, this interaction is between a protein and a shorter peptide fragment. Such peptides are often part of larger disordered regions in other proteins. The flexible nature of peptides enables the rapid...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2022-09-01
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Series: | Frontiers in Bioinformatics |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbinf.2022.959160/full |