Drebrin Isoforms Critically Regulate NMDAR- and mGluR-Dependent LTD Induction

Drebrin is an actin-binding protein that is preferentially expressed in the brain. It is highly localized in dendritic spines and regulates spine shapes. The embryonic-type (drebrin E) is expressed in the embryonic and early postnatal brain and is replaced by the adult-type (drebrin A) during develo...

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Bibliographic Details
Main Authors: Hiroki Yasuda, Nobuhiko Kojima, Kenji Hanamura, Hiroyuki Yamazaki, Kenji Sakimura, Tomoaki Shirao
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Cellular Neuroscience
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Online Access:https://www.frontiersin.org/article/10.3389/fncel.2018.00330/full