Targeting Small Molecule Delivery to the Brain and Spinal Cord via Intranasal Administration of Rabies Virus Glycoprotein (RVG29)-Modified PLGA Nanoparticles

Targeting Small Molecule Delivery to the Brain and Spinal Cord via Intranasal Administration of Rabies Virus Glycoprotein (RVG29)-Modified PLGA Nanoparticles

Alternative routes of administration are one approach that could be used to bypass the blood−brain barrier (BBB) for effective drug delivery to the central nervous system (CNS). Here, we focused on intranasal delivery of polymer nanoparticles. We hypothesized that surface modification of p...

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Bibliographic Details
Main Authors: Eugene P. Chung, Jennifer D. Cotter, Alesia V. Prakapenka, Rebecca L. Cook, Danielle M. DiPerna, Rachael W. Sirianni
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Pharmaceutics
Subjects:
intranasal
nanoparticle
brain
spinal cord
targeting
rabies virus glycoprotein
Online Access:https://www.mdpi.com/1999-4923/12/2/93

Internet

https://www.mdpi.com/1999-4923/12/2/93

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