Integrin-linked kinase mRNA expression in circulating mononuclear cells as a biomarker of kidney and vascular damage in experimental chronic kidney disease

Integrin-linked kinase mRNA expression in circulating mononuclear cells as a biomarker of kidney and vascular damage in experimental chronic kidney disease

Abstract Background Traditional biomarkers of chronic kidney disease (CKD) detect the disease in its late stages and hardly predict associated vascular damage. Integrin-linked kinase (ILK) is a scaffolding protein and a serine/threonine protein kinase that plays multiple roles in several pathophysio...

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Bibliographic Details
Main Authors: Sofía Campillo, Elena Gutiérrez-Calabrés, Susana García-Miranda, Mercedes Griera, Loreto Fernández Rodríguez, Sergio de Frutos, Diego Rodríguez-Puyol, Laura Calleros
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Cell Communication and Signaling
Subjects:
ILK
Biomarker
Renal damage
Vascular damage
Chronic kidney disease (CKD)
Online Access:https://doi.org/10.1186/s12964-024-01646-2

Internet

https://doi.org/10.1186/s12964-024-01646-2

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