Polymorphism in ASCL1 target gene DDC is associated with clinical outcomes of small cell lung cancer patients

Polymorphism in ASCL1 target gene DDC is associated with clinical outcomes of small cell lung cancer patients

Background Achaete‐scute homolog 1 (ASCL1) is a basic helix‐loop‐helix transcription factor and is essential in the differentiation of neuroendocrine cells and neural tissues. ASCL1 is frequently overexpressed in small cell lung cancer (SCLC) and plays a crucial role in the pathogenesis of SCLC. Met...

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Bibliographic Details
Main Authors: Ji Hyun Kim, Shin Yup Lee, Jin Eun Choi, Sook Kyung Do, Jang Hyuck Lee, Mi Jeong Hong, Hyo‐Gyoung Kang, Won Kee Lee, Kyung Min Shin, Ji Yun Jeong, Sun Ha Choi, Yong Hoon Lee, Hyewon Seo, Seung Soo Yoo, Jaehee Lee, Seung Ick Cha, Chang Ho Kim, Jae Yong Park
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Thoracic Cancer
Subjects:
ASCL1
clinical outcomes
DDC
polymorphism
SCLC
Online Access:https://doi.org/10.1111/1759-7714.13212

Internet

https://doi.org/10.1111/1759-7714.13212

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