Exposure of Children to Rural Lifestyle Factors Associated With Protection Against Allergies Induces an Anti-Neu5Gc Antibody Response

Exposure of Children to Rural Lifestyle Factors Associated With Protection Against Allergies Induces an Anti-Neu5Gc Antibody Response

Rural lifestyle has been shown to be highly protective against the development of allergies. Contact to farm-animals or pets and early-life consumption of milk products turned out to be important. These exposures provide contact to N-glycolylneuraminic acid (Neu5Gc), a sialic acid naturally expresse...

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Bibliographic Details
Main Authors: Remo Frei, Caroline Roduit, Ruth Ferstl, Liam O'Mahony, Roger P. Lauener
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-07-01
Series:Frontiers in Immunology
Subjects:
N-glycolylneuraminic acid
asthma
regulatory T cells
anti-inflammatory
animal contact
hygiene hypothesis
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.01628/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.01628/full

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