Mouse Models for Exploring the Biological Consequences and Clinical Significance of <i>PIK3CA</i> Mutations

The phosphatidylinositol 3-kinase (PI3K) pathway is involved in a myriad of cellular signalling pathways that regulate cell growth, metabolism, proliferation and survival. As a result, alterations in the PI3K pathway are frequently associated with human cancers. Indeed, <i>PIK3CA</i>&...

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Bibliographic Details
Main Authors: Camilla B. Mitchell, Wayne A. Phillips
Format: Article
Language:English
Published: MDPI AG 2019-04-01
Series:Biomolecules
Subjects:
Online Access:https://www.mdpi.com/2218-273X/9/4/158