Mouse Models for Exploring the Biological Consequences and Clinical Significance of <i>PIK3CA</i> Mutations
The phosphatidylinositol 3-kinase (PI3K) pathway is involved in a myriad of cellular signalling pathways that regulate cell growth, metabolism, proliferation and survival. As a result, alterations in the PI3K pathway are frequently associated with human cancers. Indeed, <i>PIK3CA</i>&...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2019-04-01
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Series: | Biomolecules |
Subjects: | |
Online Access: | https://www.mdpi.com/2218-273X/9/4/158 |