Opioid analgesia alters corticospinal coupling along the descending pain system in healthy participants

Opioids are potent analgesic drugs with widespread cortical, subcortical, and spinal targets. In particular, the central pain system comprising ascending and descending pain pathways has high opioid receptor densities and is thus crucial for opioid analgesia. Here, we investigated the effects of the...

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Bibliographic Details
Main Authors: Alexandra Tinnermann, Christian Sprenger, Christian Büchel
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2022-04-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/74293