Examining the Role of Hypothalamus-Derived Neuromedin-U (NMU) in Bone Remodeling of Rats

Examining the Role of Hypothalamus-Derived Neuromedin-U (NMU) in Bone Remodeling of Rats

Global loss of the neuropeptide Neuromedin-U (NMU) is associated with increased bone formation and high bone mass in male and female mice by twelve weeks of age, suggesting that NMU suppresses osteoblast differentiation and/or activity in vivo. NMU is highly expressed in numerous anatomical location...

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Bibliographic Details
Main Authors: Gabriella Born-Evers, Ashley L. Orr, Elizabeth Q. Hulsey, Maria E. Squire, Julia M. Hum, Lilian Plotkin, Catherine Sampson, Jonathan Hommel, Jonathan W. Lowery
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Life
Subjects:
osteoblast
bone
Neuromedin U
NMU
Online Access:https://www.mdpi.com/2075-1729/13/4/918

Internet

https://www.mdpi.com/2075-1729/13/4/918

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