A novel tumor mutational burden-based risk model predicts prognosis and correlates with immune infiltration in ovarian cancer

A novel tumor mutational burden-based risk model predicts prognosis and correlates with immune infiltration in ovarian cancer

Tumor mutational burden (TMB) has been reported to determine the response to immunotherapy, thus affecting the patient’s prognosis in many cancers. However, it is unclear whether TMB or TMB-related signature could be used as prognostic indicators for ovarian cancer (OC), as its potential association...

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Bibliographic Details
Main Authors: Haoyu Wang, Jingchun Liu, Jiang Yang, Zhi Wang, Zihui Zhang, Jiaxin Peng, Ying Wang, Li Hong
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Immunology
Subjects:
weighted gene correlation network analysis
risk model
ovarian cancer
gene signature
tumor mutational burden (TMB)
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.943389/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.943389/full

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