The role and therapeutic significance of the anoikis pathway in renal clear cell carcinoma

Anoikis is a specialized mode of programmed cell death. Specifically, once cells detach from the original extracellular matrix, an apoptotic program is initiated, preventing colonization of the cells in distant parts of the organ. Therefore, both distant metastasis and colonization of cancer cells r...

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Bibliographic Details
Main Authors: Jin Wang, Xiaochen Qi, Qifei Wang, Guangzhen Wu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Oncology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2022.1009984/full