Prevalence of PALB2 mutations in breast cancer patients in multi-ethnic Asian population in Malaysia and Singapore.

Prevalence of PALB2 mutations in breast cancer patients in multi-ethnic Asian population in Malaysia and Singapore.

BACKGROUND: The partner and localizer of breast cancer 2 (PALB2) is responsible for facilitating BRCA2-mediated DNA repair by serving as a bridging molecule, acting as the physical and functional link between the breast cancer 1 (BRCA1) and breast cancer 2 (BRCA2) proteins. Truncating mutations in t...

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Bibliographic Details
Main Authors: Sze Yee Phuah, Sheau Yee Lee, Peter Kang, In Nee Kang, Sook-Yee Yoon, Meow Keong Thong, Mikael Hartman, Jen-Hwei Sng, Cheng Har Yip, Nur Aishah Mohd Taib, Soo-Hwang Teo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3748013?pdf=render

Internet

http://europepmc.org/articles/PMC3748013?pdf=render

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